Canada Med Stop Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Available 7 Days a Week


Express shipping

May be available upon request

Lowest Price, Guaranteed

match price or beat it by 10% *

Life-Time Free shipping

Find out if you're eligible!

  • Delivery time is between 8-14 business days.
  • Express shipping may be available upon request


Activella contains the medicinal ingredient called estradiol, which is a form of estrogen, a female sex hormone that governs many of the bodily processes in the female body. The other medicinal component found in Activella is called norethindrone, which is a form of progesterone, another female hormone that regulates the process of ovulation and menstruation in the female body.

Activella is used as treatment with other medications to relieve the symptoms associated with menopause such as hot flashes and vaginal changes while preventing osteoporosis as well.

Activella is a prescription medication and should be taken strictly as directed by your prescribing doctor.

Taking estradiol has a potential risk of developing a condition that may ultimately result in uterine cancer. If you notice any abnormal bleeding in your vagina while on treatment with Activella, you should inform your doctor of this immediately.

During treatment, you should have regular consultations with your doctor to monitor your progress in order to judge whether you should continue or stop treatment. Make it a practice to self-examine your breasts for lumps every month and schedule a mammogram annually while using Activella.


Before starting treatment with Activella, you should consult with your doctor regarding your medical history, especially if you have had unusual vaginal bleeding that remains unchecked, liver disease, a bleeding disorder, heart attack, stroke, blood clot, or cancer of the breast, uterus, cervix, or vagina.

To ensure your safety during treatment, also inform your doctor if you have had a history of heart disease, liver problems, jaundice, hereditary angioedema, epilepsy, kidney disease, gallbladder disease, asthma, migraines, lupus, porphyria, endometriosis or uterine fibroid tumors, thyroid disorder, or high calcium levels in the blood.

Side Effects

There are both common (less serious) and uncommon (serious) side effects associated with the use of Activella. If you have any concerns about any side effects you are experiencing, contact your doctor.

Some common side effects of Activella may include:

  • Nausea
  • Vomiting
  • Bloating
  • Stomach cramps
  • Fluid retention
  • Headache
  • Breast pain
  • Thinning scalp hair
  • Vaginal itching or discharge
  • Menstrual cycle changes
  • Breakthrough bleeding

Uncommon, yet serious side effects may include:

  • Heart attack symptoms
  • Stroke symptoms
  • Blood clot symptoms
  • Stomach swelling
  • Tenderness
  • Jaundice
  • Cognitive impairment
  • Confusion
  • Abnormal behavior
  • Abnormal bleeding
  • Pelvic pain
  • Breast lump
  • High calcium levels in the blood

If you notice any uncommon side effects listed here, seek emergency medical assistance and call your doctor right away.


Can I smoke cigarettes during treatment with Activella?

Do not smoke when using Activella as it may seriously increase the potential risk of blood clots, stroke, or a heart attack.

How should I store my Activella when I’m not using it?

When it’s time to store your Activella medication, keep them in a cool, dry, and dark environment safely out of reach from young children and pets.

Hear From People Like You

Don't just take our word, listen to real customers whose lives have changed for the better.

Real People, Trustworthy Reviews

See what others are saying about their experience!

Sally D

March 14, 2023

Meds arrived quickly, probably because they came from Canada. In good shape.

Dwayne M

March 14, 2023


Pamela V

March 14, 2023

I am always very pleased with being able to order from Medicare will only cover half the year and then I am in the donut hole....Xarelto works very well for my A-Fib and because of you I can use all year long

Nancy M

March 14, 2023

The representatives are excellent in customer service. I have used this drug company for many years. The price of my prescription is the reason I use Canada Meds.

Carolyn W

March 14, 2023

good interaction and very helpful

Carol K

March 14, 2023

I have used Canada Med Stop for about 10 years. My orders have always been efficiently handled and approved by my doctors. Plus the cost of my prescription has been a 3rd of the cost in the US.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-202-1513 and a member of our CareTeam will be happy to assist you.

Call 1-877-202-1513
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.