Canadian Meds Pharmacy > Activella (Estradiol & Norethindrone) - Known as Activelle Internationally
DON’T MISS THE Price Drop! For Activella (Estradiol & Norethindrone) - Known as Activelle Internationally or Activella (Estradiol & Norethindrone) - Known as Activelle LD Internationally
Please enter a valid Email.

Buy Activella

1. Strength


2. Quantity

Activella (Estradiol & Norethindrone) - Known as Activelle Internationally
QTY Price Unit Price Select
28 $62.00 $2.21 BUY
56 $93.00 $1.66 BUY
84 $102.00 $1.21 BUY
Activella (Estradiol & Norethindrone) - Known as Activelle LD Internationally
QTY Price Unit Price Select
Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-202-1513 and a member of our CareTeam will be happy to assist you.

Call 1-877-202-1513 Questions? Let's Chat
Real Customers, Honest Reviews

Activella contains the medicinal ingredient called estradiol, which is a form of estrogen, a female sex hormone that governs many of the bodily processes in the female body. The other medicinal component found in Activella is called norethindrone, which is a form of progesterone, another female hormone that regulates the process of ovulation and menstruation in the female body.

Activella is used as treatment with other medications to relieve the symptoms associated with menopause such as hot flashes and vaginal changes while preventing osteoporosis as well.


Activella is a prescription medication and should be taken strictly as directed by your prescribing doctor.

Taking estradiol has a potential risk of developing a condition that may ultimately result in uterine cancer. If you notice any abnormal bleeding in your vagina while on treatment with Activella, you should inform your doctor of this immediately.

During treatment, you should have regular consultations with your doctor to monitor your progress in order to judge whether you should continue or stop treatment. Make it a practice to self-examine your breasts for lumps every month and schedule a mammogram annually while using Activella.


Before starting treatment with Activella, you should consult with your doctor regarding your medical history, especially if you have had unusual vaginal bleeding that remains unchecked, liver disease, a bleeding disorder, heart attack, stroke, blood clot, or cancer of the breast, uterus, cervix, or vagina.

To ensure your safety during treatment, also inform your doctor if you have had a history of heart disease, liver problems, jaundice, hereditary angioedema, epilepsy, kidney disease, gallbladder disease, asthma, migraines, lupus, porphyria, endometriosis or uterine fibroid tumors, thyroid disorder, or high calcium levels in the blood.

Side Effects

There are both common (less serious) and uncommon (serious) side effects associated with the use of Activella. If you have any concerns about any side effects you are experiencing, contact your doctor.

Some common side effects of Activella may include:

  • Nausea
  • Vomiting
  • Bloating
  • Stomach cramps
  • Fluid retention
  • Headache
  • Breast pain
  • Thinning scalp hair
  • Vaginal itching or discharge
  • Menstrual cycle changes
  • Breakthrough bleeding

Uncommon, yet serious side effects may include:

  • Heart attack symptoms
  • Stroke symptoms
  • Blood clot symptoms
  • Stomach swelling
  • Tenderness
  • Jaundice
  • Cognitive impairment
  • Confusion
  • Abnormal behavior
  • Abnormal bleeding
  • Pelvic pain
  • Breast lump
  • High calcium levels in the blood

If you notice any uncommon side effects listed here, seek emergency medical assistance and call your doctor right away.


Can I smoke cigarettes during treatment with Activella?

Do not smoke when using Activella as it may seriously increase the potential risk of blood clots, stroke, or a heart attack.

How should I store my Activella when I’m not using it?

When it’s time to store your Activella medication, keep them in a cool, dry, and dark environment safely out of reach from young children and pets.

IMPORTANT NOTE: The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
IMPORTANT NOTE: Please note that not all medications, including any referenced on this page, are dispensed from our affiliated Canadian pharmacy. The medications in your order may be filled and shipped from an approved International fulfillment center located in a country other than Canada. In addition to dispensing medications from our Canadian pharmacy, medication orders are also filled and shipped from international fulfillment centers that are approved by the regulatory bodies from their respective countries. Medication orders are filled and shipped from approved fulfillment centers around the world including, but not limited to, Canada, Singapore, United Kingdom, New Zealand, Turkey, Mauritius, India, Australia, and the United States. The items in your order may be filled and shipped from any one of the above jurisdictions. The products are sourced from various countries including, but not limited to, Canada, United Kingdom, New Zealand, Turkey, India, Australia, and the United States. All of our affiliated fulfillment centers have been approved by the regulatory bodies from their respective countries.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

What's the difference between generic drugs and brand name drugs?

What's the difference between the branded products you sell and the ones I get locally?
The branded drugs we sell are chemically and therapeutically no different from the ones you get in your local pharmacy. They both generally come from the same exact manufacturer. Generally, the main difference* is in the packaging and the price. Our packaging may be different from what you get locally, but we're also much cheaper.

* Other differences may include differences in trade name, form, and general appearance.

Why are there packaging differences?
Due to differences in government regulation, different countries have different packaging requirements. For example, a product in Canada (or any other country) will have different packaging than the same product in the US even though both drugs are chemically and therapeutically equivalent and are generally manufactured by the same exact company.

Why are your drugs so much cheaper?
Due to government price controls, medications from Canada and many other countries are often significantly cheaper than in the United States. Also, other countries may have more affordable generic versions of drugs, which may not yet be available in the US.

1-877-202-1513 HAVE A QUESTION? CHAT