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Alphagan P (brimonidine) is a prescription eye drop medication that is used to treat people who suffer from open-angle glaucoma or ocular hypertension. It works by reducing fluid build-up in the eye, which would lead to lowering the pressure inside the eye.

Strictly follow your prescribing doctor’s instructions when using brimonidine eye drops. Make sure your hands are thoroughly disinfected and washed before handling the eye drops.

The recommended method of applying brimonidine eye drops is to squeeze a drop in your lower eyelid by pulling it down to create a small pocket. Then, keep your eyes closed for a couple of minutes while tilting your head down. Gently apply pressure on the inside corner of your eyes for about one minute to prevent drainage into your tear ducts.


If you are currently using other eye drop medications, make sure you wait five minutes before or after the use of brimonidine eye drops.

If you notice that your eyes are becoming swollen, painful, or have a discharge, immediately stop using this medication.

To ensure the safety of use of brimonidine eye drops, make sure your doctor is aware if you have ever had heart complications, circulation problems, low blood pressure, depression, Raynaud’s syndrome, and Buerger disease.

Side Effects

There is a possibility you may experience unwanted side effects of brimonidine eye drops. Some of the common side effects that can develop are:

  • Mild itching
  • Redness
  • Burning
  • Eye irritation
  • Dry mouth
  • Blurry vision
  • Drowsiness
  • Tiredness

There are more dangerous side effects of brimonidine eye drops that are less likely to occur, which may include:

  • Eye pain
  • Increased watering
  • Vision changes
  • Severe swelling
  • Redness
  • Burning
  • Discomfort in or around your eye


Is it normal for my Alphagan P eye drops to look cloudy?

If you notice that the contents of your brimonidine eye drops look cloudy, changed colors, or has visible particles in it, dispose of the medication and use a new bottle.

Is there any special way to store my Alphagan P eye drops?

When you’re not using your brimonidine eye drops, safely store the bottle in a dry and cool environment out of the reach of children and pets.

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