Canadian Meds Pharmacy > Premarin Vaginal Cream
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Premarin Cream (Conjugated Estrogens)
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14g X 1 $50.00 BUY
14g X 2 $76.00 BUY
14g X 3 $95.00 BUY
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Premarin Cream contains a combination of estrogen hormones. Estrogen is the primary female sex hormone produced by the ovaries that are responsible for many of the core processes in the female body.

This medication is applied directly inside the vagina to treat menopausal symptoms in females such as dryness, burning, irritation, and pain during sexual intercourse.

There are other uses for Premarin Cream that may not be mentioned here.


It is imperative that you use Premarin Cream the way that you were instructed to by your prescribing doctor. Importantly, not using the cream in greater or lesser doses or for a longer period of time than instructed to.

When taking conjugated estrogens, the possibility of developing a condition that has a chance of resulting in uterine cancer is increased. Your physician may deem necessary to prescribe you for a progestin to use in combination with Premarin Cream to mitigate this risk. If you notice any abnormal bleeding in the vagina, you should inform your physician of this at once.

Do not apply Premarin Cream using your fingers and only use the vaginal applicator provided to you. After using the applicator, take it apart and cleanse it thoroughly with warm water with the use of a light soap. Avoid using extremely hot or boiling water, as the plastic may lose its shape and intended functionality.

Get routine checks with your doctor to measure if the Premarin Cream is working effectively to relieve your symptoms and whether this medication is right for you. Make it a monthly routine to check your breasts for lumps and schedule mammograms on a regular basis.

You may need to stop your treatment if you are scheduled to have a major surgical operation or need to be on long-term bed rest. Always inform any doctor or surgeon that you are using Premarin Cream.

When not using this medication, always keep it out of the reach of young children and pets in a cool and dry environment.


Take precautions before using Premarin Cream. If you had a medical history of abnormal bleeding in the vagina that has not been looked at, liver disease, heart attack, stroke, blood clot, hormone-related cancer, breast cancer, vaginal cancer, uterine/cervical cancer or if you have a higher risk of developing blood clots because of a heart problem or a family history of blood disorder.

If you are pregnant, you should not use Premarin Cream. If you think you might be pregnant, inform your doctor immediately.

If you are not yet past menopause, speak to your doctor about the best contraceptive options available to you during your treatment with Premarin Cream. This medication has a possibility of weakening the latex material used in condoms, diaphragm, or cervical cap.

While using Premarin Cream, you are at risk of blood clots, a stroke, or heart attack, and an even greater risk if you have a history of high blood pressure, diabetes, high cholesterol levels, if you are overweight, or if you smoke.

Estrogen may increase the likelihood of developing heart disease, stroke, breast cancer, uterine cancer, ovarian cancer, or dementia. It is also likely to slow the production of breast milk and you should speak to your doctor if you are currently breastfeeding.

Inform your doctor of your complete medical history to determine if Premarin Cream is right for you, especially if you have had a hysterectomy, heart disease, liver problems, jaundice, kidney disease, gallbladder disease, asthma, epilepsy, migraines, lupus, endometriosis, hereditary angioedema, porphyria, thyroid disorder, or high calcium levels in your blood.

Premarin Cream is only approved to be used by adults over the age of eighteen.

Side Effects

If you notice symptoms such as hives, breathing difficulties, face swelling, lips swelling, tongue swelling, or throat swelling while using Premarin Cream, you may be having an allergic reaction. Call for emergency medical assistance.

Contact your doctor immediately if you notice signs of a heart attack, stroke, blood clot, or high calcium levels in your blood. These symptoms consist of but are not limited to, chest pain, pressure in the chest, jaw pain, shoulder pain, nausea, sweating, numbness, weakness, severe headache, slurring of words, cognitive impairment, vision loss, short of breath, tenderness in stomach, jaundice, memory problems, confusion, unusual behavior, abnormal vaginal bleeding, pelvic pain, a lump in your breast, vomiting, constipation, increased thirst or increased urination, muscle weakness, bone pain, or fatigue.

More common side effects from the use of Premarin Cream are:

  • Headaches
  • Pain in the pelvis
  • Feeling warm
  • Redness in your skin
  • Tingly sensation
  • Breast pain
  • Vaginal itching
  • Vaginal discharge
  • Breakthrough bleeding
  • Changes in your menstrual cycles

This is not a complete list of all possible side effects you may experience. You should consult with your physician if you have any questions or concerns.


Is there anything I should avoid while using Premarin Cream?

Try not to smoke cigarettes. This has been known to immensely increase the possibility of developing blood clots, having a stroke or a heart attack during the use of Premarin Cream.

What should I do if I missed my dose?

Try to take the dose you missed when you realize. Unless it is close to the time for your next dose. Never try to make up for a dose you missed by taking more than you are prescribed to take.

IMPORTANT NOTE: The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
IMPORTANT NOTE: Please note that not all medications, including any referenced on this page, are dispensed from our affiliated Canadian pharmacy. The medications in your order may be filled and shipped from an approved International fulfillment center located in a country other than Canada. In addition to dispensing medications from our Canadian pharmacy, medication orders are also filled and shipped from international fulfillment centers that are approved by the regulatory bodies from their respective countries. Medication orders are filled and shipped from approved fulfillment centers around the world including, but not limited to, Canada, Singapore, United Kingdom, New Zealand, Turkey, Mauritius, India, Australia, and the United States. The items in your order may be filled and shipped from any one of the above jurisdictions. The products are sourced from various countries including, but not limited to, Canada, United Kingdom, New Zealand, Turkey, India, Australia, and the United States. All of our affiliated fulfillment centers have been approved by the regulatory bodies from their respective countries.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

What's the difference between generic drugs and brand name drugs?

What's the difference between the branded products you sell and the ones I get locally?
The branded drugs we sell are chemically and therapeutically no different from the ones you get in your local pharmacy. They both generally come from the same exact manufacturer. Generally, the main difference* is in the packaging and the price. Our packaging may be different from what you get locally, but we're also much cheaper.

* Other differences may include differences in trade name, form, and general appearance.

Why are there packaging differences?
Due to differences in government regulation, different countries have different packaging requirements. For example, a product in Canada (or any other country) will have different packaging than the same product in the US even though both drugs are chemically and therapeutically equivalent and are generally manufactured by the same exact company.

Why are your drugs so much cheaper?
Due to government price controls, medications from Canada and many other countries are often significantly cheaper than in the United States. Also, other countries may have more affordable generic versions of drugs, which may not yet be available in the US.

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