Zolmitriptan narrows blood vessels in the brain and is most commonly used to treat migraine headache symptoms. Zolmitriptan should not be used to treat common tension headaches or other headaches unless confirmed by a doctor.

Take zolmitriptan when you notice migraine symptoms; the regular tablet is taken with a full glass of water. The orally disintegrating tablet should only be opened from its blister pack when you need it. If headache does not go away or comes back, take a second tablet after 2 hours. Do not take more than 10mg of this drug in 24 hours. Contact your doctor if: symptoms do not improve after the maximum dose, symptoms don’t go away at all, if medication seems to stop working or working as well.

Do not use zolmitriptan if you have used a MAO inhibitor in the last 14 days, or within 24 hours of another migraine headache medication, such as zolmitriptan nasal spray or ergot medicine. Do not use if you have hypertension, heart problems,circulation issues, Wolff-Parkinson-White syndrome, a different headache. Inform your doctor if you have epilepsy, seizures, liver/kidney disease, coronary heart disease or risk factors, or if you have phenylketonuria. Inform your doctor if you take cimetidine. Use caution when driving or doing anything that requires alertness.

Zolmitriptan may raise blood pressure to dangerous levels, so it may need to be checked regularly. Find emergency help if you suspect an overdose, allergic reaction, or other severe reaction including, but not limited to: tightness in jaw/neck/throat/chest, rapid pulse, dizziness, sudden and severe stomach pain, heart attack symptoms, symptoms of high serotonin. Other common side effects include: pain/tightness in throat/chest, upset stomach, drymouth, pressure/heavy feeling, drowsiness, fatigue, flushing.